Baker Bros. Advisors LP

Track record

How each disclosed position did against the S&P ~6 months later

The outcome curve and every position's resultPro →

+73.2%

median move per position

+7.9%

S&P 500 median, same spans

5 of 5

beat the S&P ~6mo later

Disclosed positions

Estimated from their latest filings — positions may have changed since

Estimated positions from their latest filingsPro →

Activity

Open-market buy & sell volume

BuySell

Total +$334.45M bought · −$1.06M sold

All filings on record

Every Form 4 transaction we track for this filer

All10Buys0Sells0

Stock	Transaction	Date	~6mo vs S&P
INCYINCYTE CORP	Grant — · 1,642 sh	2026-06-08	—
INCYINCYTE CORP	Grant — · 1,642 sh	2026-06-08	—
KNSAKiniksa Pharmaceuticals International, plc	Grant — · 6,078 sh	2026-05-29	—
KNSAKiniksa Pharmaceuticals International, plc	Grant — · 6,078 sh	2026-05-29	—
ACADACADIA PHARMACEUTICALS INC	Grant — · 18,622 sh	2026-05-29	—
ACADACADIA PHARMACEUTICALS INC	Grant — · 18,622 sh	2026-05-29	—
BCYCBICYCLE THERAPEUTICS PLC	Grant — · 19,000 sh	2026-01-02	—
BCYCBICYCLE THERAPEUTICS PLC	Grant — · 19,000 sh	2026-01-02	—
INCYINCYTE CORP	Grant — · 328 sh	2025-12-31	—
INCYINCYTE CORP	Grant — · 328 sh	2025-12-31	—

INCYGrant

2026-06-08 · INCYTE CORP

1,642

—

INCYGrant

2026-06-08 · INCYTE CORP

1,642

—

KNSAGrant

2026-05-29 · Kiniksa Pharmaceuticals International, plc

6,078

—

KNSAGrant

2026-05-29 · Kiniksa Pharmaceuticals International, plc

6,078

—

ACADGrant

2026-05-29 · ACADIA PHARMACEUTICALS INC

18,622

—

ACADGrant

2026-05-29 · ACADIA PHARMACEUTICALS INC

18,622

—

BCYCGrant

2026-01-02 · BICYCLE THERAPEUTICS PLC

19,000

—

BCYCGrant

2026-01-02 · BICYCLE THERAPEUTICS PLC

19,000

—

INCYGrant

2025-12-31 · INCYTE CORP

328

—

INCYGrant

2025-12-31 · INCYTE CORP

328

—

Newest 10 of 114 filings·Every Form 4 on record, with outcomesPro →

Filing in the same companies

Other insiders active in these names in the last 3 years

TE

Thompson Elizabeth H.Z.

ACAD · IGMS · last 2026-07-30

HE

Harrigan Edmund

ACAD · INCY · last 2026-06-30

DJ

Daly James M

ACAD · MDGL · last 2026-05-29

LR

Levy Richard S

KNSA · MDGL · last 2026-05-22

HH

Hoppenot Herve

BCYC · INCY · last 2026-01-02

FJ

Fouse Jacqualyn A

INCY · MDGL · last 2025-06-20

Outcomes measure each position — the first buy in a stock and every buy within 182 days — against the closing price ~6 months (120 trading days) later, with the S&P 500 over the same span for context. Pre-scheduled 10b5-1 plan trades are excluded from the record. Positions are estimated from the latest reported post-transaction holdings, split-adjusted, at the latest close. Built from SEC Form 4 filings and market prices — past outcomes, not predictions or advice.